SB525334
SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.
| Trivial name | N/A |
| Catalog Number | S1476 |
| Molecular Formula | C18H16BrN5S |
| CAS# | 356559-20-1 |
| Inchi | InChI=1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1 |
| Inchi Key | AZKSAVLVSZKNRD-UHFFFAOYSA-M |
| SMILES | CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-] |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/SB-525334.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB525334-chemical-structure-S1476.gif |