SB525334
SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.
| Trivial name | N/A |
| Catalog Number | S1476 |
| Molecular Formula | C14H15BrClNO6 |
| CAS# | 356559-20-1 |
| Inchi | InChI=1S/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11+,12+,13-,14-/m1/s1 |
| Inchi Key | OPIFSICVWOWJMJ-AEOCFKNESA-N |
| SMILES | C1=CC(=C(C2=C1NC=C2OC3C(C(C(C(O3)CO)O)O)O)Cl)Br |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/SB-525334.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB525334-chemical-structure-S1476.gif |