SB525334
SB525334 is a potent and selective inhibitor of TGFβ receptor I (ALK5) with IC50 of 14.3 nM in a cell-free assay, 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6.
| Trivial name | N/A |
| Catalog Number | S1476 |
| Molecular Formula | C20H18N2O2 |
| CAS# | 356559-20-1 |
| Inchi | InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3 |
| Inchi Key | VOFUROIFQGPCGE-UHFFFAOYSA-N |
| SMILES | CCN(CC)C1=CC2=C(C=C1)N=C3C4=CC=CC=C4C(=O)C=C3O2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/SB-525334.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SB525334-chemical-structure-S1476.gif |