GSK256066
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
| Trivial name | N/A |
| Catalog Number | S2620 |
| Molecular Formula | C27H26N4O5S |
| CAS# | 801312-28-7 |
| Inchi | InChI=1S/C27H26N4O5S/c1-16-11-21(37(34,35)20-10-5-7-17(12-20)27(33)31(2)3)14-22-24(16)29-15-23(26(28)32)25(22)30-18-8-6-9-19(13-18)36-4/h5-15H,1-4H3,(H2,28,32)(H,29,30) |
| Inchi Key | JFHROPTYMMSOLG-UHFFFAOYSA-N |
| SMILES | CC1=CC(=CC2=C(C(=CN=C12)C(=O)N)NC3=CC(=CC=C3)OC)S(=O)(=O)C4=CC=CC(=C4)C(=O)N(C)C |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/gsk256066.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GSK256066-chemical-structure-S2620.gif |