GSK256066
GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.
| Trivial name | N/A |
| Catalog Number | S2620 |
| Molecular Formula | C21H20N2O2S.HCl |
| CAS# | 801312-28-7 |
| Inchi | InChI=1S/C21H20N2O2S.ClH/c1-11-9-16(24)17(14-5-3-13(4-6-14)12(2)10-22)18-15-7-8-26-20(15)21(25)23-19(11)18;/h3-9,12,24H,10,22H2,1-2H3,(H,23,25);1H/t12-;/m0./s1 |
| Inchi Key | CQPRMBOOBXSZSP-YDALLXLXSA-N |
| SMILES | Cl.CC(CN)C1=CC=C(C=C1)C2=C3C(=C(C)C=C2O)NC(=O)C4=C3C=CS4 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/gsk256066.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GSK256066-chemical-structure-S2620.gif |