WYE-354
WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM, blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) not P-AKT (T308), selective for mTOR than PI3Kα (> 100-fold) and PI3Kγ (> 500-fold).
| Trivial name | / |
| Catalog Number | CSN16829 |
| Alternative Name(s) | / |
| Research Area | Cancer |
| Molecular Formula | C24H29N7O5 |
| CAS# | 1062169-56-5 |
| Purity | ≥98% |
| SMILES | O=C(N1CCC(N2N=CC3=C(N4CCOCC4)N=C(C5=CC=C(NC(OC)=O)C=C5)N=C32)CC1)OC |
| Size | 5mg |
| Supplier Page | https://www.csnpharm.com/products/wye-354.html |