BVT 948
BVT 948 is a non-competitive, cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) with IC50 of 0.09 – 1.7 μM, displaying irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP. BVT 948 enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo.
| Trivial name | / |
| Catalog Number | CSN25337 |
| Alternative Name(s) | / |
| Research Area | Cancer |
| Molecular Formula | C14H11NO3 |
| CAS# | 39674-97-0 |
| Purity | ≥98% |
| SMILES | O=C(C(C)(C)C1=C2O)N=C1C3=CC=CC=C3C2=O |
| Size | 5mg |
| Supplier Page | https://www.csnpharm.com/products/4-hydroxy-3,3-dimethyl-2h-benzo[g]indole-2,5(3h)-dione.html |