RON-IN-1
c-Met/RON Dual Kinase Inhibitor is a potent inhibitor against the kinase activities of HGF receptor c-Met and MSP (Macrophage Stimulating Protein) receptor RON with IC50 of 4 and 9 nM, respectively, and it is reported to inhibit NIH3T3 TRP-Met and U-87 tumor growth in mice in vivo in a dose-dependent manner.
| Trivial name | AMG-1 |
| Catalog Number | CSN25585 |
| Alternative Name(s) | AMG-1 |
| Research Area | Cancer |
| Molecular Formula | C31H29FN4O5 |
| CAS# | 913376-84-8 |
| Purity | ≥98% |
| SMILES | O=C(C1=C(C)N(CC(C)(O)C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=CC=C45)C(F)=C3 |
| Size | 50mg |
| Supplier Page | https://www.csnpharm.com/products/n-(3-fluoro-4-((7-methoxyquinolin-4-yl)oxy)phenyl)-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazole-4-carboxamide.html |