FG-7142
FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex .
| Trivial name | ZK 39106; LSU-65 |
| Catalog Number | CSN27585 |
| Alternative Name(s) | ZK 39106; LSU-65 |
| Research Area | inverse agonist |
| Molecular Formula | C13H11N3O |
| CAS# | 78538-74-6 |
| Purity | ≥97% |
| SMILES | O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)NC |
| Size | 10mg |
| Supplier Page | https://www.csnpharm.com/products/n-methyl-9h-pyrido[3,4-b]indole-3-carboxamide.html |