5-Fluorouridine
5-Fluorouridine is a metabolite of 5-fluorouracil with anticancer activity and cytotoxic activity. 5-fluorouridine inhibits rRNA synthesis of human colon carcinoma cells. 5-Fluorouridine exhibits cytotoxic effect on growth of L1210 cells with an IC50 of 2 nM. 5-Fluorouridine triphosphate acted as a potent competitive inhibitor of VPg uridylylation, the initial step of viral replication.
| Trivial name | 5-Fluorouracil 1β-D-ribofuranoside; FUrd |
| Catalog Number | CSN25507 |
| Alternative Name(s) | 5-Fluorouracil 1β-D-ribofuranoside; FUrd |
| Research Area | Anti-infection|Cancer |
| Molecular Formula | C9H11FN2O6 |
| CAS# | 316-46-1 |
| Purity | ≥97% |
| SMILES | O=C1NC(C(F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=O |
| Size | 100mg |
| Supplier Page | https://www.csnpharm.com/products/1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1h,3h)-dione.html |