ERRα antagonist-1
ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
| Trivial name | / |
| Catalog Number | CSN27511 |
| Alternative Name(s) | / |
| Research Area | / |
| Molecular Formula | C21H19N3S2 |
| CAS# | 1072145-33-5 |
| Purity | ≥97% |
| SMILES | C12=CC=CC=C1C(/N=C3SCCN\3C4=NCCS4)C5=CC=CC=C5C=C2 |
| Size | 100mg |
| Supplier Page | https://www.csnpharm.com/products/n-(3-(4,5-dihydrothiazol-2-yl)thiazolidin-2-ylidene)-5h-dibenzo[a,d][7]annulen-5-amine.html |