Alobresib (GS-5829)
Alobresib (GS-5829) is a novel BET inhibitor that represents a highly effective therapeutics agent against recurrent/chemotherapy-resistant USC-overexpressing c-Myc. Alobresib (GS-5829) inhibits CLL cell proliferation and induces leukemia cell apoptosis through deregulation of key signaling pathways, such as BLK, AKT, ERK1/2, and MYC. Alobresib (GS-5829) also inhibits NF-κB signaling.
Trivial name | N/A |
Catalog Number | S8961 |
Molecular Formula | C26H23N5O2 |
CAS# | 1637771-14-2 |
SMILES | CC1=C(C(=NO1)C)C2=CC(=C3C(=C2)NC(=N3)C4CC4)C(C5=CC=CC=N5)(C6=CC=CC=N6)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/alobresib.html |
Additional Information | https://file.selleck.cn/downloads/struct/s8961-alobresib-gs-5829-chemical-structure.gif |