6-Diazo-5-oxo-L-norleucine
6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1 mM for cKGA (kidney-type glutaminase). 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.
| Trivial name | Diazooxonorleucine, 6-Diazo-5-oxo-L-nor-Leucine, L-6-Diazo-5-oxonorleucine, DON |
| Catalog Number | S8620 |
| Molecular Formula | C6H9N3O3 |
| CAS# | 157-03-9 |
| SMILES | C(CC(=O)C=[N+]=[N-])C(C(=O)O)N |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/6-diazo-5-oxo-l-norleucine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s8620-6-diazo-5-oxo-l-norleucinel-don,don-chemical-structure.gif |