WT161
WT161 is a potent, selective, and bioavailable HDAC6 inhibitor with IC50 values of 0.4 nM, 8.35 nM and 15.4 nM for HDAC6, HDAC1 and HDAC2, respectively; shown to have >100-fold selectivity over other HDACs. WT161 induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S8495 |
| Molecular Formula | C27H30N4O3 |
| CAS# | 1206731-57-8 |
| Inchi | InChI=1S/C27H30N4O3/c32-26(15-9-1-2-10-16-27(33)30-34)29-28-21-22-17-19-25(20-18-22)31(23-11-5-3-6-12-23)24-13-7-4-8-14-24/h3-8,11-14,17-21,34H,1-2,9-10,15-16H2,(H,29,32)(H,30,33)/b28-21+ |
| Inchi Key | KXWWYFKVBFUVIZ-SGWCAAJKSA-N |
| SMILES | C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=CC=C(C=C3)C=NNC(=O)CCCCCCC(=O)NO |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/wt161.html |
| Additional Information | https://file.selleck.cn/downloads/struct/wt161-chemical-structure-s8495.gif |