THZ2
THZ2, a THZ1 analog, is a selective inhibitor of CDK7 with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM.
| Trivial name | N/A |
| Catalog Number | S7969 |
| Molecular Formula | C31H28ClN7O2 |
| CAS# | 1604810-84-5 |
| SMILES | CN(C)CC=CC(=O)NC1=CC=CC(=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/thz2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s7969-thz2-chemical-structure.gif |