NEM (N-Ethylmaleimide)
NEM (N-Ethylmaleimide) is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. N-Ethylmaleimide (NEM) inactivates endogenous deubiquitinating enzymes (DUBs). N-Ethylmaleimide (NEM) specifically inhibits phosphate transport in mitochondria.
Trivial name | N/A |
Catalog Number | S3692 |
Molecular Formula | C6H7NO2 |
CAS# | 128-53-0 |
Inchi | InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3 |
Inchi Key | HDFGOPSGAURCEO-UHFFFAOYSA-N |
SMILES | CCN1C(=O)C=CC1=O |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/n-ethylmaleimide-nem.html |
Additional Information | https://file.selleck.cn/downloads/struct/n-ethylmaleimide-nem-chemical-structure-s3692.gif |