Ketoconazole
Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively. Ketoconazole is an androgen biosynthesis inhibitor.
| Trivial name | R 41400 |
| Catalog Number | S1353 |
| Molecular Formula | C26H28Cl2N4O4 |
| CAS# | 65277-42-1 |
| Inchi | InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m0/s1 |
| Inchi Key | XMAYWYJOQHXEEK-OZXSUGGESA-N |
| SMILES | CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Ketoconazole.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Ketoconazole-chemical-structure-S1353.gif |