XL228
XL228 is a protein kinase inhibitor with IC50 of 5 nM, 1.4 nM, 3.1 nM, 1.6 nM, 6.1 nM and 2 nM for wild-type ABL kinase, ABL T315I, Aurora A, IGF-1R, SRC and LYN, respectively.
| Trivial name | N/A |
| Catalog Number | S1272 |
| Molecular Formula | C18H13ClF2N6O |
| CAS# | 898280-07-4 |
| Inchi | InChI=1S/C18H13ClF2N6O/c1-8-7-24-17-15(8)12(2-3-23-17)28-16-10(20)4-9(5-11(16)21)25-14-6-13(19)26-18(22)27-14/h2-7H,1H3,(H,23,24)(H3,22,25,26,27) |
| Inchi Key | NRSGWEVTVGZDFC-UHFFFAOYSA-N |
| SMILES | CC1=CNC2=NC=CC(=C12)OC3=C(C=C(C=C3F)NC4=CC(=NC(=N4)N)Cl)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/xl228.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s1272-xl228-chemical-structure.gif |