FL-411
FL-411 (BRD4-IN-1) is a potent and selective inhibitor of Bromodomain-containing protein 4 (BRD4) with IC50 of 0.43 μM for BRD4(1). FL-411 induces ATG5-dependent autophagy-associated cell death (ACD) by blocking BRD4-AMPK interaction.
Trivial name | BRD4-IN-1 |
Catalog Number | S1027 |
Molecular Formula | C18H19N3O2S |
CAS# | 2118944-88-8 |
SMILES | CC1=CC(=CC(=C1O)C)C2=NC3=C(C4=C(S3)CN(CC4)C)C(=O)N2 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/fl-411.html |
Additional Information | https://file.selleck.cn/downloads/struct/s1027-fl-411-chemical-structure.gif |