RP-64477
RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.
Trivial name | N/A |
Catalog Number | S0820 |
Molecular Formula | C29H42N2O3S |
CAS# | 135239-65-5 |
SMILES | CCCCCCCCCCOC1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C(=O)NCCCC)SC |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/rp-64477.html |
Additional Information | https://file.selleck.cn/downloads/struct/s0820-rp-64477-chemical-structure.gif |