XCT790
XCT-790 (Compound 12) is a potent and selective inverse agonist for estrogen-related receptor α (ERRα) with IC50 of 0.37 μM. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ. XCT-790 (Compound 12) significantly inhibits in vivo tumor growth and angiogenesis, and induces apoptosis.
| Trivial name | Compound 12 |
| Catalog Number | S0407 |
| Molecular Formula | C44H43ClN2O8 |
| CAS# | 725247-18-7 |
| Inchi | InChI=1S/C23H16O6.C21H27ClN2O2/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/ h1-10,24-25H,11H2,(H,26,27)(H,28,29);1-9,21,25H,10-17H2 |
| Inchi Key | ASDOKGIIKXGMNB-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.C1=CC=C2C(=C1)C=C(C(=C2CC3=C(C(=CC4=CC=CC=C43)C(=O)O)O)O)C(=O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/xct-790.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s0407-xct790-chemical-structure.gif |