L 189
L 189 is a novel human DNA ligase inhibitor with IC50 of 5 μM, 9 μM and 5 μM for hLigI, hLigIII and hLigIV, respectively. L 189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L 189 specifically sensitizes cancer cells to DNA damage.
Trivial name | N/A |
Catalog Number | S0102 |
Molecular Formula | C11H10N4OS |
CAS# | 64232-83-3 |
SMILES | C1=CC=C(C=C1)C=NC2=C(NC(=S)NC2=O)N |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/l-189.html |
Additional Information | https://file.selleck.cn/downloads/struct/s0102-l-189-chemical-structure.gif |