Umbralisib R-enantiomer
Umbralisib R-enantiomer is a delta inhibitor of PI3K and a less active enantiomer of TGR-1202. The IC50 of Umbralisib R-enantiomers against δPI3 kinase is at least 20 times lower than that of the inhibitors against other PI3K isoforms (A, β, and γ).
| Catalog Number | T13140 |
| Alternative Name(s) | TGR-1202 R-enantiomer , RP5264 R-enantiomer |
| Research Area | PI3K/Akt/mTOR signaling |
| Molecular Formula | C31H24F3N5O3 |
| CAS# | 1532533-69-9 |
| Purity | 95.61% |
| SMILES | NC1=C2C(=NN([C@H](C)C3=C(C(=O)C=4C(O3)=CC=C(F)C4)C5=CC(F)=CC=C5)C2=NC=N1)C6=CC(F)=C(OC(C)C)C=C6 |
| Size | 50 mg |
| Supplier Page | https://www.targetmol.com/compound/Umbralisib R-enantiomer |
| Additional Information | https://www.targetmol.com/datasheet/T13140 |