Berbamine
Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).
| Trivial name | BA, BBM |
| Catalog Number | S9141 |
| Molecular Formula | C37H40N2O6 |
| CAS# | 478-61-5 |
| Inchi | InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(41-3)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-31-18-23(8-11-30(31)40)17-29-35-25(13-15-39(29)2)20-34(42-4)36(43-5)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1- 5H3/t28-,29+/m0/s1 |
| Inchi Key | DFOCUWZXJBAUSQ-URLMMPGGSA-N |
| SMILES | CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/berbamine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/berbamine-chemical-structure-s9141.gif |