Triptophenolide
Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.
| Trivial name | Hypolide |
| Catalog Number | S9045 |
| Molecular Formula | C20H24O3 |
| CAS# | 74285-86-2 |
| Inchi | InChI=1S/C20H24O3/c1-11(2)12-4-6-16-14(18(12)21)5-7-17-15-10-23-19(22)13(15)8-9-20(16,17)3/h4,6,11,17,21H,5,7-10H2,1-3H3/t17-,20+/m0/s1 |
| Inchi Key | KPXIBWGPZSPABK-FXAWDEMLSA-N |
| SMILES | CC(C)C1=C(C2=C(C=C1)C3(CCC4=C(C3CC2)COC4=O)C)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/triptophenolide.html |
| Additional Information | https://file.selleck.cn/downloads/struct/triptophenolide-chemical-structure-s9045.gif |