Prim-o-glucosylcimifugin
Prim-O-glucosylcimifugin (Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside) is a major constituent in Radix Saposhnikovia that has been long used for the treatment of pyrexia, rheumatism, and cancer in traditional Chinese medicine. It shows potential anticancer activity. Prim-O-glucosylcimifugin downregulates the mRNA and protein expression inducible NO synthase (iNOS) and cyclooxygenase 2 (COX-2) in LPS-activated RAW 264.7 macrophages in a concentration-dependent manner.
Trivial name | Cimifugin beta-D-glucopyranoside, Cimifugin 7-glucoside |
Catalog Number | S9029 |
Molecular Formula | C22H28O11 |
CAS# | 80681-45-4 |
Inchi | InChI=1S/C22H28O11/c1-22(2,28)15-5-10-12(32-15)6-13-16(20(10)29-3)11(24)4-9(31-13)8-30-21-19(27)18(26)17(25)14(7-23)33-21/h4,6,14-15,17-19,21,23,25-28H,5,7-8H2,1-3H3/t14-,15+,17-,18+,19-,21-/m1/s1 |
Inchi Key | XIUVHOSBSDYXRG-UVTAEQIVSA-N |
SMILES | CC(C)(C1CC2=C(O1)C=C3C(=C2OC)C(=O)C=C(O3)COC4C(C(C(C(O4)CO)O)O)O)O |
Size | 1mg |
Supplier Page | http://www.selleckchem.com/products/prim-o-glucosylcimifugin.html |
Additional Information | https://file.selleck.cn/downloads/struct/prim-o-glucosylcimifugin-chemical-structure-s9029.gif |