Homoharringtonine (HHT)

Homoharringtonine (HHT), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.

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Trivial name	CGX-635, Omacetaxine mepesuccinate, Myelostat, NSC 141633
Catalog Number	S9015
Molecular Formula	C29H39NO9
CAS#	26833-87-4
Inchi	InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m 1/s1
Inchi Key	HYFHYPWGAURHIV-JFIAXGOJSA-N
SMILES	CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O
Size	1mg
Supplier Page	http://www.selleckchem.com/products/homoharringtonine.html
Additional Information	https://file.selleck.cn/downloads/struct/homoharringtonine-chemical-structure-s9015.gif