G10 (STING agonist-1)

G10 (STING agonist-1) is a novel human-specific STING agonist that triggers IFN regulatory factor 3 (IRF3)/ type I interferon (IFN)-associated transcription in human fibroblasts. STING agonist-1 (G10) potently reduces growth of Chikungunya virus (CHIKV) with IC90 of 8.01 μM and blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC90 of 24.57 μM.

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Trivial name	N/A
Catalog Number	S8954
Molecular Formula	C21H16ClFN2O3S
CAS#	702662-50-8
Inchi	InChI=1S/C21H16ClFN2O3S/c22-16-4-1-5-17(23)15(16)11-25-18-9-13(6-7-19(18)29-12-20(25)26)21(27)24-10-14-3-2-8-28-14/h1-9H,10-12H2,(H,24,27)
Inchi Key	NAGKYJATVFXZKN-UHFFFAOYSA-N
SMILES	C1C(=O)N(C2=C(S1)C=CC(=C2)C(=O)NCC3=CC=CO3)CC4=C(C=CC=C4Cl)F
Size	5mg
Supplier Page	http://www.selleckchem.com/products/sting-agonist-1-g10.html
Additional Information	https://file.selleck.cn/downloads/struct/sting-agonist-1-chemical-structure-s8954.gif