GMB-475
GMB-475 is a proteolysis-targeting chimera (PROTAC) that allosterically targets BCR-ABL1 protein and recruit the E3 ligase Von Hippel-Lindau (VHL), resulting in ubiquitination and subsequent degradation of the oncogenic fusion protein.
| Trivial name | N/A |
| Catalog Number | S8888 |
| CAS# | 2490599-18-1 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/gmb-475.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gmb-475-chemical-structure-s8888.gif |