PDD00017273
PDD00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50 of 26 nM. PDD00017273 exhibits >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3.
| Trivial name | N/A |
| Catalog Number | S8862 |
| Molecular Formula | C23H26N6O4S2 |
| CAS# | 1945950-21-9 |
| Inchi | InChI=1S/C23H26N6O4S2/c1-14-9-16(27(4)25-14)12-28-20-6-5-18(35(32,33)26-23(3)7-8-23)10-19(20)21(30)29(22(28)31)13-17-11-24-15(2)34-17/h5-6,9-11,26H,7-8,12-13H2,1-4H3 |
| Inchi Key | IFWUBRBMMNTBRZ-UHFFFAOYSA-N |
| SMILES | CC1=NN(C(=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN=C(S5)C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/pdd00017273.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pdd00017273-chemical-structure-s8862.gif |