MK-3903
MK-3903 is a potent and selective AMPK activator with an EC50 of 8 nM for α1 β1 γ1 subunit. It activates 10 of the 12 pAMPK complexes with EC50 values in the range of 8-40 nM and maximal activation >50%.
Trivial name | N/A |
Catalog Number | S8803 |
Molecular Formula | C27H19ClN2O3 |
CAS# | 1219737-12-8 |
Inchi | InChI=1S/C27H19ClN2O3/c1-16-7-12-20(13-21(16)26(31)32)33-27-29-24-14-22(23(28)15-25(24)30-27)19-10-8-18(9-11-19)17-5-3-2-4-6-17/h2-15H,1H3,(H,29,30)(H,31,32) |
Inchi Key | FIKQZQDYGXAUHC-UHFFFAOYSA-N |
SMILES | CC1=C(C=C(C=C1)OC2=NC3=C(N2)C=C(C(=C3)C4=CC=C(C=C4)C5=CC=CC=C5)Cl)C(=O)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/mk-3903.html |
Additional Information | https://file.selleck.cn/downloads/struct/mk-3903-chemical-structure-s8803.gif |