TH34
TH34 is a HDAC inhibitor that shows pronounced selectivity for HDACs 6, 8 and 10 over HDACs 1, 2 and 3. In a NanoBRET assay, TH34 strongly binds HDAC6, 8 and 10 with low-micromolar IC50 concentrations (HDAC6: 4.6 µM, HDAC8: 1.9 µM, HDAC10: 7.7 µM).
| Trivial name | N/A |
| Catalog Number | S8773 |
| Molecular Formula | C15H16N2O2 |
| CAS# | 2196203-96-8 |
| Inchi | InChI=1S/C15H16N2O2/c1-11-7-8-13(15(18)17-19)9-14(11)16-10-12-5-3-2-4-6-12/h2-9,16,19H,10H2,1H3,(H,17,18) |
| Inchi Key | PZBARTUEWCQNSN-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)C(=O)NO)NCC2=CC=CC=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/th34.html |
| Additional Information | https://file.selleck.cn/downloads/struct/th34-chemical-structure-s8773.gif |