AZ304
AZ304 is a synthetic inhibitor designed to interact with the ATP-binding site of wild type and V600E mutant BRAF with IC50 values of 79 nM and 38 nM, respectively. It also inhibits CRAF, p38 and CSF1R at sub 100 nM potencies.
| Trivial name | N/A |
| Catalog Number | S8755 |
| Molecular Formula | C27H25N5O2 |
| CAS# | 942507-42-8 |
| Inchi | InChI=1S/C27H25N5O2/c1-17-8-9-20(31-26(33)18-6-5-7-19(12-18)27(2,3)15-28)13-23(17)32-25-22-11-10-21(34-4)14-24(22)29-16-30-25/h5-14,16H,1-4H3,(H,31,33)(H,29,30,32) |
| Inchi Key | NGWQZRWVYYFTHC-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=NC=NC4=C3C=CC(=C4)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/az304.html |
| Additional Information | https://file.selleck.cn/downloads/struct/az304-chemical-structure-s8755.gif |