AZ32
AZ32 is a specific inhibitor of the ATM kinase that possesses good BBB penetration in mouse with an IC50 value of <0.0062 μM for ATM enzyme. It shows adequate selectivity over ATR and also has high cell permeability.
| Trivial name | N/A |
| Catalog Number | S8729 |
| Molecular Formula | C20H16N4O |
| CAS# | 2288709-96-4 |
| Inchi | InChI=1S/C20H16N4O/c1-21-20(25)16-9-7-15(8-10-16)18-11-23-19-12-22-17(13-24(18)19)14-5-3-2-4-6-14/h2-13H,1H3,(H,21,25) |
| Inchi Key | LCRTUEXVVKVKBD-UHFFFAOYSA-N |
| SMILES | CNC(=O)C1=CC=C(C=C1)C2=CN=C3C=NC(=C[N]23)C4=CC=CC=C4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/az32.html |
| Additional Information | https://file.selleck.cn/downloads/struct/az32-chemical-structure-s8729.gif |