Atuveciclib (BAY-1143572)

Atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with IC50 values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3α and GSK3β respectively.

Price Not Available 5mg Atuveciclib (BAY-1143572) Supplier Page

Trivial name	N/A
Catalog Number	S8727
Molecular Formula	C18H18FN5O2S
CAS#	1414943-88-6
Inchi	InChI=1S/C18H18FN5O2S/c1-26-16-9-13(19)6-7-15(16)17-21-11-22-18(24-17)23-14-5-3-4-12(8-14)10-27(2,20)25/h3-9,11,20H,10H2,1-2H3,(H,21,22,23,24)
Inchi Key	ACWKGTGIJRCOOM-UHFFFAOYSA-N
SMILES	COC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/atuveciclib-bay-1143572.html
Additional Information	https://file.selleck.cn/downloads/struct/atuveciclib-bay-1143572-chemical-structure-s8727.gif