Nemtabrutinib (ARQ 531)

Nemtabrutinib (ARQ 531, MK-1026) is an ATP-competitive tyrosine kinase inhibitor designed to target BTK with an IC50 of 0.85 nM. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases.

Price Not Available 25mg Nemtabrutinib (ARQ 531) Supplier Page

Trivial name	MK-1026
Catalog Number	S8711
Molecular Formula	C25H23ClN4O4
CAS#	2095393-15-8
Inchi	InChI=1S/C25H23ClN4O4/c26-21-10-17(34-16-4-2-1-3-5-16)8-9-19(21)23(32)20-11-27-24-22(20)25(29-14-28-24)30-15-6-7-18(12-31)33-13-15/h1-5,8-11,14-15,18,31H,6-7,12-13H2,(H2,27,28,29,30)/t15-,18+/m1/s1
Inchi Key	JSFCZQSJQXFJDS-QAPCUYQASA-N
SMILES	C1CC(OCC1NC2=NC=NC3=C2C(=CN3)C(=O)C4=C(C=C(C=C4)OC5=CC=CC=C5)Cl)CO
Size	25mg
Supplier Page	http://www.selleckchem.com/products/arq531.html
Additional Information	https://file.selleck.cn/downloads/struct/arq-531-chemical-structure-s8711.gif