SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively and less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2.
| Trivial name | N/A |
| Catalog Number | S8699 |
| CAS# | 1146618-41-8 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sns-314.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sns-314-mesylate-chemical-structure-s8699.gif |
SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1154 |
| Molecular Formula | C34H31CuN4Na3O6 |
| CAS# | 1057249-41-8 |
| Inchi | InChI=1S/C34H36N4O6.Cu.3Na/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23;;;;/h7,12-14,17,21H,1,8-11H2,2-6H3 ,(H5,35,36,37,38,39,40,41,42,43,44);;;;/q;+2;3*+1/p-5 |
| Inchi Key | HWDGVJUIHRPKFR-UHFFFAOYSA-I |
| SMILES | CCC1=C(C2=CC3=NC(=CC4=NC(=C(C5=NC(=C(C5=C([O-])[O-])C)C=C1[N-]2)CC(=O)[O-])C(C4C)CCC(=O)[O-])C(=C3C=C)C)C.[Na+].[Na+].[Na+].[Cu+2] |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sns-314-mesylate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sns-314-chemical-structure-s1154.gif |
