Selective JAK3 inhibitor 1

Selective JAK3 inhibitor 1 is an irreversible JAK3 inhibitor with Ki values of 0.07 nM, 320 nM, 740 nM for JAK3, JAK1 and JAK2 respectively. It is also selective over the other kinases possessing a cysteine in the same region as JAK3, such as BMX, EGFR, ITK, and BTK.

Trivial name N/A
Catalog Number S8684
Molecular Formula C19H18N4O3
CAS# 1443235-95-7
Inchi InChI=1S/C19H18N4O3/c1-4-26-19(25)14-9-20-17-15(14)16(21-10-22-17)12-6-5-7-13(8-12)23-18(24)11(2)3/h5-10H,2,4H2,1,3H3,(H,23,24)(H,20,21,22)
Inchi Key NJPHKVOXHRAPGJ-UHFFFAOYSA-N
SMILES CCOC(=O)C1=CNC2=NC=NC(=C12)C3=CC(=CC=C3)NC(=O)C(=C)C
Size 5mg
Supplier Page http://www.selleckchem.com/products/selective-jak3-inhibitor-1.html
Additional Information https://file.selleck.cn/downloads/struct/selective-jak3-inhibitor-1-chemical-structure-s8684.gif