AZD1390
AZD1390 is a first-in-class orally available and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cells and >10,000-fold selectivity over closely related members of the PIKK family of enzymes and excellent selectivity across a broad panel of kinases.
| Trivial name | N/A |
| Catalog Number | S8680 |
| Molecular Formula | C27H32FN5O2 |
| CAS# | 2089288-03-7 |
| Inchi | InChI=1S/C27H32FN5O2/c1-18(2)33-26-21-14-20(22(28)15-23(21)29-17-24(26)31(3)27(33)34)19-8-9-25(30-16-19)35-13-7-12-32-10-5-4-6-11-32/h8-9,14-18H,4-7,10-13H2,1-3H3 |
| Inchi Key | VQSZIPCGAGVRRP-UHFFFAOYSA-N |
| SMILES | CC(C)N1C2=C(C=NC3=CC(=C(C=C32)C4=CN=C(C=C4)OCCCN5CCCCC5)F)N(C1=O)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/azd1390.html |
| Additional Information | https://file.selleck.cn/downloads/struct/azd1390-chemical-structure-s8680.gif |