Tenalisib
Tenalisib is a potent and selective dual PI3Kδ/γ inhibitor with IC50 values of 24.5 nM and 33.2 nM for PI3Kδ and PI3Kγ, respectively. Its selectivity over α and β isoforms are more than 300-fold and 100-fold, respectively.
| Trivial name | RP6530 |
| Catalog Number | S8672 |
| Molecular Formula | C23H18FN5O2 |
| CAS# | 1639417-53-0 |
| Inchi | InChI=1S/C23H18FN5O2/c1-2-16(29-23-19-22(26-11-25-19)27-12-28-23)21-18(13-6-5-7-14(24)10-13)20(30)15-8-3-4-9-17(15)31-21/h3-12,16H,2H2,1H3,(H2,25,26,27,28,29)/t16-/m0/s1 |
| Inchi Key | HDXDQPRPFRKGKZ-INIZCTEOSA-N |
| SMILES | CCC(C1=C(C(=O)C2=CC=CC=C2O1)C3=CC(=CC=C3)F)NC4=NC=NC5=C4NC=N5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/tenalisib-rp6530.html |
| Additional Information | https://file.selleck.cn/downloads/struct/tenalisib-rp6530-chemical-structure-s8672.gif |