IWP-O1
IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells.
Trivial name | N/A |
Catalog Number | S8645 |
Molecular Formula | C26H20N6O |
CAS# | 2074607-48-8 |
Inchi | InChI=1S/C26H20N6O/c33-24(29-23-12-11-22(17-28-23)19-7-3-1-4-8-19)18-32-26(21-9-5-2-6-10-21)25(30-31-32)20-13-15-27-16-14-20/h1-17H,18H2,(H,28,29,33) |
Inchi Key | GYYDQHBKIHQHEB-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C2=CN=C(C=C2)NC(=O)CN3C(=C(N=N3)C4=CC=NC=C4)C5=CC=CC=C5 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/iwp-O1.html |
Additional Information | https://file.selleck.cn/downloads/struct/iwp-o1-chemical-structure-s8645.gif |