Necrostatin 2 racemate (Nec-1s)
Necrostatin 2 racemate (Nec-1s, 7-Cl-O-Nec1, Necrostatin-1 stable, Necrostatin 1S) is a stable variant of Necrostatin-1. It is a more specific RIPK1 inhibitor lacking the IDO-targeting effect, with >1000-fold more selective for RIPK1 than for any other kinase out of 485 human kinases.
Trivial name | 7-Cl-O-Nec1, Necrostatin-1 stable, Necrostatin 1S |
Catalog Number | S8641 |
Molecular Formula | C13H12ClN3O2 |
CAS# | 852391-15-2 |
Inchi | InChI=1S/C13H12ClN3O2/c1-17-12(18)10(16-13(17)19)5-7-6-15-11-8(7)3-2-4-9(11)14/h2-4,6,10,15H,5H2,1H3,(H,16,19) |
Inchi Key | WIKGAEMMNQTUGL-UHFFFAOYSA-N |
SMILES | CN1C(=O)C(NC1=O)CC2=CNC3=C2C=CC=C3Cl |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/nec-1s-7-cl-o-nec1.html |
Additional Information | https://file.selleck.cn/downloads/struct/nec-1s-7-cl-o-nec1-chemical-structure-s8641.gif |