Linrodostat (BMS-986205)
Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.
| Trivial name | ONO-7701 |
| Catalog Number | S8629 |
| CAS# | 1923833-60-6 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/bms-986205.html |
| Additional Information | https://file.selleck.cn/downloads/struct/bms-986205-chemical-structure-s8629.gif |