DCA (Sodium dichloroacetate)

DCA (Sodium dichloroacetate), a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress Na+-K+-2Cl- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth.

Price Not Available 100mg DCA (Sodium dichloroacetate) Supplier Page
Trivial name Dichloroacetic acid, bichloroacetic acid, BCA
Catalog Number S8615
Molecular Formula C2HCl2O2.Na
CAS# 2156-56-1
Inchi InChI=1S/C2H2Cl2O2.Na/c3-1(4)2(5)6;/h1H,(H,5,6);/q;+1/p-1
Inchi Key LUPNKHXLFSSUGS-UHFFFAOYSA-M
SMILES C(C(=O)[O-])(Cl)Cl.[Na+]
Size 100mg
Supplier Page http://www.selleckchem.com/products/sodium-dichloroacetate-dca.html
Additional Information https://file.selleck.cn/downloads/struct/sodium-dichloroacetate-dca-chemical-structure-S8615.gif