Repotrectinib (TPX-0005)

Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM).

Price Not Available 25mg Repotrectinib (TPX-0005) Supplier Page

Trivial name	N/A
Catalog Number	S8583
Molecular Formula	C18H18FN5O2
CAS#	1802220-02-5
Inchi	InChI=1S/C18H18FN5O2/c1-10-8-20-18(25)14-9-21-24-6-5-16(23-17(14)24)22-11(2)13-7-12(19)3-4-15(13)26-10/h3-7,9-11H,8H2,1-2H3,(H,20,25)(H,22,23)/t10-,11+/m0/s1
Inchi Key	FIKPXCOQUIZNHB-WDEREUQCSA-N
SMILES	CC1CNC(=O)C2=C3N=C(C=CN3N=C2)NC(C4=C(O1)C=CC(=C4)F)C
Size	25mg
Supplier Page	http://www.selleckchem.com/products/tpx-0005.html
Additional Information	https://file.selleck.cn/downloads/struct/TPX-0005-chemical-structure-S8583.gif