PRN1371
PRN1371 is an irreversible covalent FGFR1-4 kinase inhibitor, with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, 2, 3, 4 and CSF1R, respectively.
| Trivial name | N/A |
| Catalog Number | S8578 |
| Molecular Formula | C26H30Cl2N6O4 |
| CAS# | 1802929-43-6 |
| Inchi | InChI=1S/C26H30Cl2N6O4/c1-5-20(35)33-11-9-32(10-12-33)7-6-8-34-24-16(15-30-26(29-2)31-24)13-17(25(34)36)21-22(27)18(37-3)14-19(38-4)23(21)28/h5,13-15H,1,6-12H2,2-4H3,(H,29,30,31) |
| Inchi Key | PUIXMSRTTHLNKI-UHFFFAOYSA-N |
| SMILES | CNC1=NC=C2C=C(C(=O)N(C2=N1)CCCN3CCN(CC3)C(=O)C=C)C4=C(C(=CC(=C4Cl)OC)OC)Cl |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/prn1371.html |
| Additional Information | https://file.selleck.cn/downloads/struct/prn1371-chemical-structure-s8578.gif |