CEP-40783 (RXDX-106)
CEP-40783 (RXDX-106) is an orally-available, potent and selective TAM(TYRO3, AXL, MER)/Met (c-Met) inhibitor displaying low nanomolar biochemical activity and slow (T1/2 >120 min) inhibitor off-rate in peptide phosphorylation assays and in vitro kinase binding assays, respectively.
Trivial name | N/A |
Catalog Number | S8570 |
Molecular Formula | C31H26F2N4O6 |
CAS# | 1437321-24-8 |
Inchi | InChI=1S/C31H26F2N4O6/c1-17(2)36-16-22(30(39)37(31(36)40)20-8-5-18(32)6-9-20)29(38)35-19-7-10-26(23(33)13-19)43-25-11-12-34-24-15-28(42-4)27(41-3)14-21(24)25/h5-17H,1-4H3,(H,35,38) |
Inchi Key | FKCWHHYUMFGOPY-UHFFFAOYSA-N |
SMILES | CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)F |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/rxdx-106-cep-40783.html |
Additional Information | https://file.selleck.cn/downloads/struct/RXDX-106-CEP-40783-chemical-structure-S8570.gif |