Seletalisib (UCB-5857)
Seletalisib (UCB-5857) is a novel small-molecule inhibitor of PI3Kδ with an IC50 value of 12 nM and shows significant selectivity to PI3Kδ with respect to the other class I PI3K isoforms (between 24- and 303-fold).
Trivial name | N/A |
Catalog Number | S8560 |
Molecular Formula | C23H14ClF3N6O |
CAS# | 1362850-20-1 |
Inchi | InChI=1S/C23H14ClF3N6O/c24-16-6-1-4-13-10-15(18(31-19(13)16)14-5-3-9-33(34)11-14)21(23(25,26)27)32-22-20-17(29-12-30-22)7-2-8-28-20/h1-12,21H,(H,29,30,32)/t21-/m1/s1 |
Inchi Key | LNLJHGXOFYUARS-OAQYLSRUSA-N |
SMILES | C1=CC2=CC(=C(N=C2C(=C1)Cl)C3=C[N+](=CC=C3)[O-])C(C(F)(F)F)NC4=NC=NC5=C4N=CC=C5 |
Size | 2mg |
Supplier Page | http://www.selleckchem.com/products/seletalisib-ucb-5857.html |
Additional Information | https://file.selleck.cn/downloads/struct/seletalisib-ucb-5857-chemical-structure-s8560.gif |