AZ31
AZ31 is a selective and novel ATM inhibitor with an IC50 of <0.0012 μM. It shows excellent selectivity over closely related enzymes (>500 fold selective over DNA-PK and PI3Kα and >1000 fold selective over mTOR, PI3Kβ and PI3Kγ).
Trivial name | N/A |
Catalog Number | S8556 |
Molecular Formula | C24H28N4O3 |
CAS# | 2088113-98-6 |
Inchi | InChI=1S/C24H28N4O3/c1-15(16-7-9-31-10-8-16)28-23-20-11-17(18-3-5-19(14-30-2)26-12-18)4-6-22(20)27-13-21(23)24(25)29/h3-6,11-13,15-16H,7-10,14H2,1-2H3,(H2,25,29)(H,27,28)/t15-/m0/s1 |
Inchi Key | DISRGUXSEDBDDN-HNNXBMFYSA-N |
SMILES | CC(C1CCOCC1)NC2=C3C=C(C=CC3=NC=C2C(=O)N)C4=CN=C(C=C4)COC |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/az31.html |
Additional Information | https://file.selleck.cn/downloads/struct/az31-chemical-structure-s8556.gif |