Belizatinib (TSR-011)
“Belizatinib (TSR-011) is a potent inhibitor of ALK (IC50=0.7 nM) and tropomyosin receptor kinase (TRK) (IC50 values less than 3 nM for TRK A, B, and C).
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Trivial name | N/A |
Catalog Number | S8511 |
Molecular Formula | C33H44FN5O3 |
CAS# | 1357920-84-3 |
Inchi | InChI=1S/C33H44FN5O3/c1-21(2)35-30(40)24-8-12-27(13-9-24)39-29-19-22(20-38-17-15-25(16-18-38)33(3,4)42)5-14-28(29)36-32(39)37-31(41)23-6-10-26(34)11-7-23/h5-7,10-11,14,19,21,24-25,27,42H,8-9,12-13,15- 18,20H2,1-4H3,(H,35,40)(H,36,37,41)/t24-,27+ |
Inchi Key | WSTUJEXAPHIEIM-FEGDYQJNSA-N |
SMILES | CC(C)NC(=O)C1CCC(CC1)N2C3=C(C=CC(=C3)CN4CCC(CC4)C(C)(C)O)N=C2NC(=O)C5=CC=C(C=C5)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/tsr-011-belizatinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/tsr-011-belizatinib-chemical-structure-S8511.gif |