Navarixin (SCH-527123)
Navarixin (SCH-527123, MK-7123, PS-291822) is a potent, orally bioavailable CXCR2/CXCR1 antagonist with IC50 values of 2.6 nM and 36 nM, respectively.
| Trivial name | MK-7123, PS-291822 |
| Catalog Number | S8506 |
| Molecular Formula | C21H23N3O5 |
| CAS# | 473727-83-2 |
| Inchi | InChI=1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1 |
| Inchi Key | RXIUEIPPLAFSDF-CYBMUJFWSA-N |
| SMILES | CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/sch-527123.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sch-527123-chemical-structure-s8506.gif |